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Illustration showing chimeric antigen receptor (CAR) T cells (blue) being used to treat plasma cell leukaemia (dark purple cells). CAR-T cells are a patient's own T cells, a form of white blood cell, that have been genetically modified to recognise and destroy certain cancer or autoimmune cells that might otherwise be tolerated by the immune system. Plasma cell leukaemia is a rare form of multiple myeloma that affects white blood cells known as plasma cells. The plasma cells become abnormal and cancerous, divide and multiply, and create large quantities of abnormal antibodies