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Secretion and mode of action of insulin in a non-diabetic person. Ingestion of a sugary food causes an increase in blood sugar. This causes the secretion of insulin by the pancreas, which is sent to the various organs of the body to stimulate the use of glucose, mainly to the muscles and liver. Thus, the glucose will either be transformed into glycogen to be stored in the liver and muscles, or used by the other organs. This will then lower the blood glucose level. Please note: this illustration does not show glucose metabolism in its entirety, but only the functions affected by diabetes mellitus