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The mayapple (Podophyllum peltatum) is a perennial herbaceous plant native to eastern North America, commonly found in woodlands and along forest edges. #Medicinal: The rhizome contains podophyllotoxin, used historically in Native American and folk medicine as a purgative, emetic, or treatment for warts. Modern derivatives are used in chemotherapy (e.g., etoposide for cancer treatment) and topical treatments for warts. # Culinary: Ripe fruit can be eaten sparingly or used in jellies, but unripe fruit and other plant parts are toxic and cause severe gastrointestinal distress. # Ornamental: Sometimes grown in shade gardens for its attractive foliage. # Vintage etching circa late 19th century. Digital restoration by Pictore. Authentic illustration free of AI